Resources
The Rametrix® Technology, Inc. Team is committed to rigorous review of our data and products. We publish the results of our studies that support product development in the leading peer-reviewed scientific, medical, and engineering journals. These published papers can be accessed by following the links.
Bhonsle, S, Bonaker, M, Neal, R, Aardema, C, Robertson, J, Howarth, J, Kavnoudias, H, Thomson, K, Goldberg, N, Davalos, R, “Characterization of irreversible electroporation with a validated perfused organ model,” J Vasc Interv Radiol 2016; 27:1913–1922 http://dx.doi.org/10.1016/j.jvir.2016.07.012
Carswell, W, Guruli, G, Tracy, A, Xu, Y, Du, P, Senger, R, Robertson, J, “Raman Spectroscopy as a non-cytological detection and quantification urinalysis method for microhematuria in human urine” (accepted, 4 30 2021, Applied Spectroscopy)
Fisher, AK, Carswell, WF, Athamaneh, AIM, Sullivan, MC, Robertson, JL, Bevan, DR, Senger, RS, “The RametrixTM LITE Toolbox v1.0 for MATLAB®,” J Raman Spectro 49 (5): 885-896, 2018
Gao, Z, Du, P, Jin, R, Robertson, J, “Surface temperature monitoring in liver procurement via functional variance Change Point Analysis,” J Amer Stat Assoc 164: 2018, published on-line July 11, 2018 DOI: 10.1080/01621459.2018.1442341
Gao, Z, Shang, Z, Du, P, Robertson, JL, “Variance change point detection under a smoothly-changing mean trend with application to liver procurement,” J American Statistical Association,” Published On-line March 8, 2018 DOI: 10.1080/01621459.2018.1442341
Gazia, C, Tamburini, R, Asthana, Ca, Chaimoy, D, Muir, S, Marino, D, Delbono, L, Viliani, V, Perin, L, DiNardo, P, Robertson, J, Orlando, G, “Extracellular matrix-based hydrogels obtained from human tissues: a work still in progress, “ Current Opin Organ Transplant 24(5): 604-612, 2019
Huttanus, H, Martinez, G, Coogan, H, Zhang, S, Donaghy, T, Du, P, Karageorge, L, Robertson, J, Senger, R, “The effects of sterile-filtration on urine molecular composition and degradation when analyzed by Raman Chemometric Urinalysis (Rametrix™)” (in preparation, text and tables available on request)
Huttanus, H, Vu, T, Guruli, G, Tracey, A, Carswell, W, Said, N, Du, P, Parkinson, B, Orlando, G, Robertson, J, Senger, R, “Raman Chemometric Urinalysis (Rametrix™) as a screen for bladder cancer,” PLoS One. 2020; 15(8): e0237070. Published online 2020 Aug 21. doi: 10.1371/journal.pone.0237070
Issa, AS, Lee, WT, Senger, RS, Kablinger, A, Trestman, R, Robertson, JL, “Detection of diluted controlled substances using a computational Raman spectroscopy technology (Rametrix®): Potential use in Point-Of-Care management of diversion” (in preparation, J Amer Pharm Assoc; text and tables available on request)
Issa, A, Senger, RS, Du, P, De la Torre Campos, D, Carswell, W, Webster, K, Sullivan, M, Gong, J, Robertson, J, “Assessment of urine specimen storage conditions using Raman Chemometric Urinalysis™ (Rametrix™),” (in preparation, J Appl Spec; text and tables available on request)
Kavuru, V, Vu, T, Karageorge, L, Choudhury, D, Senger, R, Robertson, J, “Dipstick analysis of urine chemistry: benefits and limitations of dry chemistry-based assays,” Postgrad Med Published on-line Oct 19 2019 https://doi.org/10.1080/00325481.2019.1679540
Kavuru, V, Senger, RS, Robertson, JL, Choudhury, D, “Analysis of urine Raman spectra differences from patients with diabetes mellitus and renal pathologies,” (submitted, Peer J)
Lake-Bakaar, G, Robertson, J, Aardema, C, “The effect of obeticholic acid on hepatic blood flow in isolated, perfused porcine liver: Correction of oxygen-nutrient mismatch might be a putative mechanism of action in NASH,” Clinical Translational Discovery (on line) 21 July 2022 https://doi.org/10.1002/ctd2.98
Lan, Q, Chen, X, Li, M, Robertson, J, Lei, Y, Jin, R, “Improving assessment in kidney viability forecasting by multitask general path model in transplantation,” Computer Methods and Programs in Biomedicine, December 2023
Lan, Q, Li, Y, Robertson, J, Jin, R, “Modeling of pre-transplant liver viability with Spatial-Temporal Smooth Variable Selection (STSVS),” Computer Methods and Programs in Biomedicine 208, Sept, 2021 (on-line, July 10, 2021) https://doi.org/10.1016/j.cmpb.2021.106264
Lan, Q, Sun, H, Deng, X, Robertson, J, Jin, R, “Non-invasive assessment of liver quality in transplantation based on thermal imaging analysis,” Computer Methods and Programs in Biomedicine 164: 31-47, 2018
O’Brien, T, Roghanizad, A, Jones, P, Aardema, C, Robertson, J, Diller, T, “The development of a thin-filmed, non-invasive tissue perfusion sensor to quantify capillary pressure occlusion of explanted organs,” IEEE Transactions in Biomedical Engineering, 64(7):1631-1637, 2017
O’Brien, T, Bonakdar, M, Bhonsle, S, Neal II, R, Aardema, C, Robertson, J, Goldberg, S. Davalos, R, “Effects of internal electrode cooling on irreversible electroporation using a perfused organ model, “ Int. J Hyperthermia, Online 5 28 18
Orlando, G, Asthana A, Tamburrini, R, Chaimov, D, Walker, SJ, Van Dyke, M, Tommei, A, Lablanche, S, Robertson, JL, Opara, E, Soker, S, “Comprehensive characterization of the human pancreatic proteome for bioengineering applications,” Biomaterials 270: 120613, https://doi.org/10.1016/j.biomaterials.2020.120613
On-line: December 16, 2020
Orlando G, Senger R, Sayed Issa A, Gutierrez AM, Jay CC, McCracken E, Farney A, Stratta R, Webb C, Davies HB, Doty T, McPherson G, Monetti A, Savino J, Byers L, Fallahzadeh M, Reeves-Daniel A, Sakhovskaja N, Asthana A, Yoza B, Bussolati B, Mikhailov A, Peveri E, Ngo L, Gage F, Fisher R, Robertson J “Raman spectroscopy-based urine molecular fingerprinting: a novel method for predicting and monitoring delayed graft function, submitted for publication]
Peloso, A, Petrosyan, A, Da Sacco, S, Booth, C, Zambon, JP, O’Brien, T, Aardema, C, Robertson, J, Rogers, J, Farney, AC, Soker, S, Stratta, RJ, Perin, L, Orlando, G,, “Renal ECM scaffolds from discarded kidneys as a platform for kidney bioengineering and regeneration: Assessing vascular morphometry, ex vivo vascular resilience and angiogenic potential,” Transplantation, On-Line, May 25, 2015, doi: 10.1097/TP.0000000000000811
Robertson, J, Senger, R et al., “Personalized Hemodialysis (PHD): An online treatment monitoring and adjustment system”
Robertson, J, Senger, R, Talty, J, Du, P, Issa, AS, Avellar, M, Ngo, L, Gomez, M, Guruli, G, “Alterations in the molecular composition of urine from COVID19 patients, detected using Raman spectroscopic and computational analysis,” (submitted, PLoS One)
Rossi, A, Asthana, A, Riganti, C, Sedrakyan, S. Byers, LN, Robertson, J, Senger, R, Montali, F, Grange, C, Porporato, PE, Aardema, C, Palles, C, Thornton, M, Petrosyan, A, Da Sacco, S, Perin, L, Orlando, G, Bussolati, B, “Artificial mitochondria transfer to mitigate ischemic damage in an In Vitro model of renal tubular injury and in an Ex Vivo porcine model of DCD renal transplantation,” (in preparation for publication)
Rossi, A, Asthana, A, Riganti, C, Sedrakyan, S. Byers, LN, Robertson, J, Senger, R, Montali, F, Grange, C, Porporato, PE, Aardema, C, Palles, C, Thornton, M, Petrosyan, A, Da Sacco, S, Perin, L, Orlando, G, Bussolati, B, “”Mitochondria transplantation mitigates damage in an In Vitro model of renal tubular Injury and in an Ex Vivo model of DCD renal transplantation,” Ann Surg. 2023 Dec; 278(6): e1313–e1326. Published online 2023 Jul 14. doi: 10.1097/SLA.0000000000006005PMCID: PMC10631499
Sano, M, Neal, RE, Garcia, PA, Gerber, D, Robertson, J, Davalos, RV, “Toward the creation of decellularized organ constructs using irreversible electroporation and active mechanical perfusion,” BioMed Engineering OnLine 9:83, 2010
Senger, R, Kavuru, V, Sullivan, M, Gouldin, A, Lundgren, S, Merrifield, K, Steen, C, Baker, E, Vu, T, Agnor, B, Martinez, G, Coogan, H, Carswell, W, Karageorge, L, Dev, D, Du, P, Sklar, A, Pirkle, J, Orlando, G, Lianos, E, Robertson, JL, “Spectral characteristics of urine specimens from healthy human volunteers analyzed using Raman Chemometric Urinalysis (Rametrix™),” PLoS One, Published: September 27, 2019 https://doi.org/10.1371/journal.pone.0222115
Senger, R, Robertson, J, “The Rametrix PRO ™ Toolbox V1.0 for MATLAB®,” Peer J, 3:35799:2:0, 2019 https://peerj.com/articles/8179
Senger, R, Sayed Issa, A, Agnor, B, Talty, J, Hollis, A, Robertson, JL, “Disease-associated multimolecular signature in the urine of patients with Lyme disease, detected using Raman spectroscopy and chemometrics (Rametrix™)” (accepted 4 25 2021), Applied Spectroscopy)
Senger, RS, Scherr, D. “Resolving complex phenotypes with Raman spectroscopy and chemometrics.” Curr Opin. Biotechnol. 2020. 66: 277-282. doi:10.1016/j.copbio.2020.09.007
Senger, R, Sullivan, M, Gouldin, A, Lundgren, S, Merrifield, K, Steen, C, Baker, E, Vu, T, Agnor, B, Martinez, G, Coogan, H, Carswell, W, Kavuru, V, Karageorge, L, Dev, D, Du, P, Sklar, A, Pirkle, J, Gulich, S, Lianos, E, Orlando, G, Robertson, JL, “Spectral characteristics of urine from patients with end-stage kidney disease, analyzed using Raman Chemometric Urinalysis (Rametrix™),” PLoS One, Published: January 10, 2020; pone.0227281
Singh, M, Tong, Y, Webster, K, Cesewski, E, Haring, AP, Laheri, S, Carswell, W, O’Brien, TJ, Aardema, CA, Senger, R, Robertson, JL, Johnson, BN, “3D printed conformal microfluidics for isolation and profiling of biomarkers from whole organs, Lab on a Chip 17: 2561-2571, 2017
Xu, Y, Du, P, Senger, R, Robertson, J, “Sparse logistic regression on functional data,” (accepted, 6 16 2021, Stat Interface)
Xu, Y, Du, P, Senger, R, Robertson, J, Pirkle, J “ISREA: An efficient peak-preserving baseline correction algorithm for Raman spectra,” Appl Spectro 75: 34-45, 2021
Zu, TNKK, Athamneh, AIM, Collakova, E, Robertson, J, Hawken, T, Aardema, C, Senger, RS, “Assessment of ex vivo perfused liver health by Raman spectroscopy.” Journal of Raman Spectroscopy. 46:551-8, 2015